Folding Control and Unfolding Free Energy of Yeast Iso-1-cytochrome c Bound to Layered Zirconium Phosphate Materials Monitored by Surface Plasmon Resonance

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Folding control and unfolding free energy of yeast iso-1-cytochrome c bound to layered zirconium phosphate materials monitored by surface plasmon resonance.

The free energy change (Delta G degrees ) for the unfolding of immobilized yeast iso-1-cytochrome c (Cyt c) at nanoassemblies was measured by surface plasmon resonance (SPR) spectroscopy. Data show that SPR is sensitive to protein conformational changes, and protein solid interface exerts a major influence on bound protein stability. First, Cyt c was self-assembled on the Au film via the single...

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Structural Characteristics of Stable Folding Intermediates of Yeast Iso-1-Cytochrome-c

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structural characteristics of stable folding intermediates of yeast iso-1-cytochrome-c

cytochrome-c (cyt-c) is an electron transport protein, and it is present throughout the evolution. more than 280 sequences have been reported in the protein sequence database (www.uniprot.org). though sequentially diverse, cyt-c has essentially retained its tertiary structure or fold. thus a vast data set of varied sequences with retention of similar structure and function makes it a primary ca...

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ژورنال

عنوان ژورنال: The Journal of Physical Chemistry B

سال: 2008

ISSN: 1520-6106,1520-5207

DOI: 10.1021/jp7121642